FAK Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730082

Product Details

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FAK protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Abstract: PTK2 Products

Synonyms: FADK Protein, FAK Protein, FAK1 Protein, FRNK Protein, PPP1R71 Protein, p125FAK Protein, pp125FAK Protein, PTK2 Protein, Fadk Protein, mKIAA4203 Protein, fak Protein, fak1a Protein, ptk2 Protein, ptk2a Protein, wu:fa18c04 Protein, zgc:66114 Protein, CG10023 Protein, CT28129 Protein, DFAK Protein, DFak Protein, DFak56 Protein, Dfak Protein, Dfak56 Protein, DmFAK Protein, Dmel\\CG10023 Protein, Fak56 Protein, Fak56D Protein, fak56 Protein, protein tyrosine kinase 2 Protein, protein tyrosine kinase 2 L homeolog Protein, PTK2 protein tyrosine kinase 2 Protein, protein tyrosine kinase 2ab Protein, Focal adhesion kinase Protein, PTK2 Protein, ptk2.L Protein, Ptk2 Protein, ptk2ab Protein, Fak Protein

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

Molecular Weight: 121.5 kDa

NCBI Accession: NP_005598

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling