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SERPINC1 Protein (Myc-DYKDDDDK Tag)

SERPINC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731823
  • Target See all SERPINC1 Proteins
    SERPINC1 (Serpin Family C Member 1 (SERPINC1))
    Protein Type
    Recombinant
    Origin
    • 13
    • 4
    • 3
    • 2
    • 1
    Human
    Source
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SERPINC1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SERPINC1 / Antithrombin-III protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SERPINC1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SERPINC1 (Serpin Family C Member 1 (SERPINC1))
    Alternative Name
    Serpinc1,antithrombin-III (SERPINC1 Products)
    Synonyms
    AT3 Protein, AT3D Protein, ATIII Protein, THPH7 Protein, SERPINC1 Protein, DKFZp470C1733 Protein, AI114908 Protein, At-3 Protein, At3 Protein, ANTITHROMBIN, AT-III Protein, AT-III Protein, serpin family C member 1 Protein, antithrombin-III Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, SERPINC1 Protein, CpipJ_CPIJ000472 Protein, CpipJ_CPIJ013111 Protein, Serpinc1 Protein
    Background
    The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
    Molecular Weight
    49 kDa
    NCBI Accession
    NP_000479
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