PAI1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PAI1 Protein (Myc-DYKDDDDK Tag) (ABIN2731824)
Target
See all PAI1 (SERPINE1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PAI1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SERPINE1 / PAI1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 1-402) protein (GST tag)
SERPINE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 86-185) protein (GST tag)SERPINE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Plasminogen Activator Inhibitor 1 (SERPINE1) protein (His tag)SERPINE1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) protein (His tag)SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) protein (His tag)SERPINE1 Origin: Pig Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) protein (His tag)SERPINE1 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Alternative Name
- Serpine1,pai1
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Background
- This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 42.7 kDa
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NCBI Accession
- NP_000593
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Pathways
- p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Target
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