SFTPB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731916

Product Details

Target: SFTPB (Surfactant Protein B (SFTPB))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SFTPB protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SFTPB (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SFTPB (Surfactant Protein B (SFTPB))

Alternative Name: Sftpb (SFTPB Products)

Synonyms: PSP-B Protein, SFTB3 Protein, SFTP3 Protein, SMDP1 Protein, SP-B Protein, AI562151 Protein, SF-B Protein, Sftp-3 Protein, Sftp3 Protein, Sp-b Protein, SFTPB Protein, sftpb Protein, xSP-B Protein, surfactant protein B Protein, surfactant associated protein B Protein, surfactant, pulmonary-associated protein B L homeolog Protein, SFTPB Protein, Sftpb Protein, sftpb.L Protein

Background: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010].

Molecular Weight: 39.5 kDa

NCBI Accession: NP_942140