SIAH2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732023

Product Details

Target: SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SIAH2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SIAH2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))

Alternative Name: Siah2 (SIAH2 Products)

Synonyms: hSiah2 Protein, Xsiah-2 Protein, siah2-A Protein, xsiah2 Protein, AA415433 Protein, Sinh2 Protein, siah E3 ubiquitin protein ligase 2 Protein, siah E3 ubiquitin protein ligase 2 L homeolog Protein, seven in absentia 2 Protein, SIAH2 Protein, siah2.L Protein, Siah2 Protein

Background: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.

Molecular Weight: 34.4 kDa

NCBI Accession: NP_005058