SMAD7 Protein (Myc-DYKDDDDK Tag)
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- Target See all SMAD7 Proteins
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SMAD7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SMAD7 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SMAD7 Protein
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SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) protein (GST tag)
SMAD7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-426) protein (Strep Tag)Crystallography grade SMAD7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-426) protein (Strep Tag)Crystallography grade SMAD7 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Alternative Name
- Smad7 (SMAD7 Products)
- Synonyms
- CRCS3 Protein, MADH7 Protein, MADH8 Protein, Smad7a Protein, Madh7 Protein, Smad10 Protein, madh7 Protein, xsmad7 Protein, wu:fj60c10 Protein, SMAD family member 7 Protein, SMAD family member 7 L homeolog Protein, SMAD7 Protein, Smad7 Protein, smad7.L Protein, smad7 Protein
- Background
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 46.2 kDa
- NCBI Accession
- NP_005895
- Pathways
- Interferon-gamma Pathway, Cell-Cell Junction Organization
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