SMARCE1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732241

Product Details

Target: SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SMARCE1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SMARCE1 / BAF57 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))

Alternative Name: Smarce1,baf57 (SMARCE1 Products)

Synonyms: BAF57 Protein, XBaf57 Protein, MGC52696 Protein, MGC69429 Protein, MGC81726 Protein, SMARCE1 Protein, DKFZp459O2235 Protein, fb54d11 Protein, wu:fb33d02 Protein, wu:fb54d11 Protein, Baf57 Protein, 2810417B20Rik Protein, 5830412H02Rik Protein, 9030408N19Rik Protein, Baf27 Protein, RGD1304726 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog Protein, smarce1 Protein, SMARCE1 Protein, smarce1.L Protein, Smarce1 Protein

Background: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Molecular Weight: 46.5 kDa

NCBI Accession: NP_003070

Pathways: Chromatin Binding