SOX2 Protein (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for SOX2 Protein (Myc-DYKDDDDK Tag) (ABIN2732450)
Target
See all SOX2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SOX2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SOX2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 155-245) protein (GST tag)
SOX2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) protein (GST tag)SOX2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-200) protein (His tag)SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 129-317) protein (His-IF2DI Tag)SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317), (full length) protein (His-SUMO Tag)SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." in: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Alternative Name
- Sox2
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Background
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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Molecular Weight
- 34.1 kDa
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NCBI Accession
- NP_003097
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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