SRA1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732656

Product Details

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SRA1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SRA1 / SRAP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: Sra1,srap (SRA1 Products)

Synonyms: SRA Protein, SRAP Protein, STRAA1 Protein, pp7684 Protein, AA959952 Protein, Sra Protein, Srap Protein, Straa1 Protein, Strra1 Protein, zgc:86613 Protein, steroid receptor RNA activator 1 Protein, steroid receptor RNA activator 1 S homeolog Protein, cytoplasmic FMR1 interacting protein 1 Protein, SRA1 Protein, Sra1 Protein, sra1 Protein, sra1.S Protein, CYFIP1 Protein

Background: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Molecular Weight: 25.5 kDa

NCBI Accession: NP_001030312

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development