TRIOBP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all TRIOBP products
- TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TRIOBP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TRIOBP / TARA (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
- Alternative Name
- Triobp,tara (TRIOBP Products)
- Synonyms
- tara Protein, DFNB28 Protein, TARA Protein, dJ37E16.4 Protein, AI428493 Protein, EST478828 Protein, Tara Protein, mKIAA1662 Protein, TRIO and F-actin binding protein Protein, TRIO and F-actin-binding protein Protein, TRIO and F-actin binding protein L homeolog Protein, TRIO and F-actin binding protein-like Protein, TRIOBP Protein, LOC100354753 Protein, triobp.L Protein, TRIOBPL Protein, Triobp Protein
- Background
- This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
- Molecular Weight
- 47.4 kDa
- NCBI Accession
- NP_619538
- Pathways
- Regulation of Actin Filament Polymerization
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