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VPREB3 Protein (Myc-DYKDDDDK Tag)

VPREB3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735411
  • Target See all VPREB3 Proteins
    VPREB3 (Pre-B Lymphocyte 3 (VPREB3))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This VPREB3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human VPREB3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product VPREB3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    VPREB3 (Pre-B Lymphocyte 3 (VPREB3))
    Alternative Name
    Vpreb3 (VPREB3 Products)
    Synonyms
    8HS-20 Protein, Vpreb-3 Protein, AI528709 Protein, VPREB3 Protein, 8HS20 Protein, N27C7-2 Protein, pre-B lymphocyte gene 3 Protein, V-set pre-B cell surrogate light chain 3 Protein, pre-B lymphocyte 3 Protein, Ig lambda-6 chain C region Protein, Vpreb3 Protein, VPREB3 Protein, LOC698694 Protein
    Background
    The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.
    Molecular Weight
    13.5 kDa
    NCBI Accession
    NP_037510
    Pathways
    Production of Molecular Mediator of Immune Response
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