VPS72 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735434

Product Details

Target: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This VPS72 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human VPS72 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Alternative Name: Vps72 (VPS72 Products)

Synonyms: CG4621 Protein, Dmel\\CG4621 Protein, dYL-1 Protein, vps72 Protein, MGC82727 Protein, Vps72 Protein, YL-1 Protein, ACYPI009531 Protein, Tcfl1 Protein, CFL1 Protein, Swc2 Protein, TCFL1 Protein, YL1 Protein, si:dkeyp-24a7.1 Protein, CG4621 gene product from transcript CG4621-RB Protein, vacuolar protein sorting 72 homolog L homeolog Protein, potential vacuolar protein sorting protein Protein, vacuolar protein sorting 72 homolog Protein, vacuolar protein sorting-associated protein 72 homolog Protein, vacuolar protein sorting 72 Protein, vacuolar protein sorting 72 homolog S homeolog Protein, vacuolar protein sorting 72 homolog (S. cerevisiae) Protein, YL-1 Protein, vps72.L Protein, VPS72 Protein, Vps72 Protein, vps72.S Protein, vps72 Protein

Background: The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Molecular Weight: 40.4 kDa

NCBI Accession: NP_005988

Pathways: Stem Cell Maintenance