CBP Protein (His tag)
-
- Target See all CBP (CREBBP) Proteins
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Mouse
-
Source
- Insect cells (Sf21)
- Purification tag / Conjugate
- This CBP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse full-length CREB-binding protein fused at the C-terminus to a His-tag.
- Purity
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product CREBBP Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
~50-100ng are required for standard HAT assay.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50-100 mM imidazole and 10 % glycerol.
- Storage
- -20 °C,-80 °C
- Storage Comment
-
Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Expiry Date
- 6 months
-
- Target
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- Alternative Name
- CREB-Binding Protein (CREBBP Products)
- Synonyms
- CBP Protein, KAT3A Protein, RSTS Protein, AW558298 Protein, CBP/p300 Protein, p300/CBP Protein, RTS Protein, cbp Protein, crebbp Protein, kat3a Protein, rsts Protein, hmm291030 Protein, Nejire Protein, CREB binding protein Protein, CREB binding protein L homeolog Protein, histone acetyltransferase p300 Protein, CREBBP Protein, Crebbp Protein, crebbp.L Protein, LOC100123220 Protein
- Background
- CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
- UniProt
- P45481
- Pathways
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
-