DEFB103A Protein

Catalog No. ABIN2830510

Product Details

Target: DEFB103A (Defensin, beta 103A (DEFB103A))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Sequence: GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK

Characteristics: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by anti-microbial activity against E.coli. is less than 30 μg/mL, corresponding to a specific activity of ＞ 33.3 IU/mg.

Purity: >98 % as determined by SDS-PAGE and HPLC.

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 20 mM PB, pH 7.4, 130 mM NaCl

Storage: -20 °C

Target Details

Target: DEFB103A (Defensin, beta 103A (DEFB103A))

Alternative Name: DEFB103A (DEFB103A Products)

Synonyms: BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, DEFB103B Protein, defensin beta 103A Protein, defensin beta 103B Protein, defensin, beta 103A Protein, beta-defensin 103 Protein, DEFB103A Protein, DEFB103B Protein, LOC694235 Protein, LOC100359096 Protein

Background: Relevance: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {ECO:0000269|PubMed:11085990}.
Synonyms: Beta-defensin 3, DEFB-3, HBD3, hBD-3, Defensin, beta 103

Molecular Weight: 5.2 kDa

UniProt: P81534

Pathways: Production of Molecular Mediator of Immune Response