C1QBP Protein (AA 75-282) (His tag)

Catalog No. ABIN2870643

Product Details

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Protein Type: Recombinant

Protein Characteristics: AA 75-282

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This C1QBP protein is labelled with His tag.

Sequence: AA 75-282

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.6 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Alternative Name: HABP1 (C1QBP Products)

Synonyms: SF2 Protein, X38k Protein, gC1qR Protein, C1QBP Protein, GC1QBP Protein, HABP1 Protein, SF2p32 Protein, gC1Q-R Protein, p32 Protein, AA407365 Protein, AA986492 Protein, D11Wsu182e Protein, P32 Protein, gC1qBP Protein, Habp1 Protein, complement C1q binding protein Protein, complement component 1, q subcomponent binding protein S homeolog Protein, complement component 1, q subcomponent binding protein Protein, C1QBP Protein, c1qbp.S Protein, LOC100227158 Protein, C1qbp Protein

Background: Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP), a member of the MAM33 family, is also known as ASF/SF2-associated protein p32, glycoprotein gC1qBP (C1qBP), mitochondrial matrix protein p32 and hyaluronan-binding protein 1, which is a homotrimer that contains three monomers forming a donut-shaped structure with an unusually asymmetric charge distribution on the surface. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. C1QBP has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. Furthermore, C1QBP has been shown to interact with Protein kinase D1, BAT2, PRKCD, PKC alpha and Protein kinase Mζ .

Molecular Weight: 24.6 kDa

NCBI Accession: NP_001203

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly