ELAVL4 Protein (His tag)
(1 reference)-
- Target See all ELAVL4 Proteins
- ELAVL4 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ELAVL4 protein is labelled with His tag.
- Application
- ELISA, Western Blotting (WB)
- Purification
- Expressed in E.Coli and purified by affinity chromatography
- Purity
- > 95%
- Endotoxin Level
- less than 0.1 ng/µg (1 IEU/µg)
- Top Product
- Discover our top product ELAVL4 Protein
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ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 312-380) protein (GST tag)
ELAVL4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 1-385) protein (Strep Tag)Crystallography grade ELAVL4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 1-380) protein (His tag)Crystallography grade ELAVL4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ELAVL4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Detection of anti-Hu paraneoplastic antibodies via WB or ELISA assay. Identification of regulatory elements in mRNA.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Storage buffer PBS, pH 7.2
- Storage
- -20 °C
- Storage Comment
- Heat stable , shipped at ambient temp. Upon delivery aliquot and store in fridge , longterm storage at -20°C.
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: "Purification and properties of HuD, a neuronal RNA-binding protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11518-24, (1996) (PubMed).
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: "Purification and properties of HuD, a neuronal RNA-binding protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11518-24, (1996) (PubMed).
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- Target
- ELAVL4 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4))
- Alternative Name
- ELAV-like protein 4 (ELAVL4 Products)
- Synonyms
- HUD Protein, PNEM Protein, HuD Protein, RGD1561943 Protein, r-HuD Protein, elrd Protein, hud Protein, wu:fc24h01 Protein, Elav Protein, Hud Protein, elrD Protein, elrD1 Protein, elrD2 Protein, ELAV-like protein 4 Protein, ELAV like RNA binding protein 4 Protein, ELAV like neuron-specific RNA binding protein 4 Protein, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) Protein, ELAV like neuron-specific RNA binding protein 4 L homeolog Protein, LOC100282339 Protein, LOC100284149 Protein, ELAVL4 Protein, Elavl4 Protein, elavl4 Protein, elavl4.L Protein
- Background
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HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene.
The HuD/ELAVL4 protein is an RNA-binding protein.
HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.
HuD was originaly discovered as the paraneoplastic antigen expressed in neuroendocrine tumors. Recombinant HuD was first used to assay the presence of anti-Hu antibodies and thereby diagnose the presence of small cell lung cancer and subacute sensory neuronopathy. In normal cells , it functions to regulate gene expression and the recombinant protein has been used to identify regualtory elements in mRNA. - Molecular Weight
- 66 kDa
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