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PCSK9 Protein (AA 1-678) (GST tag)

PCSK9 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN3013383
  • Target See all PCSK9 Proteins
    PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-678
    Origin
    • 18
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 26
    • 7
    • 6
    • 2
    • 1
    Wheat germ
    Purification tag / Conjugate
    This PCSK9 protein is labelled with GST tag.
    Application
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    Purpose
    PCSK9 (Human) Recombinant Protein (P01)
    Sequence
    MGTVSSRRSW WPLPLLLLLL LLLLGPAGAR AQEDEDGLVE APEPGTTATF HRCAKDPWRL PGTYVVVLKE ETHLSQSERT ARRLQAQAAR RGYLTKILHV FHGLLPGFLV KMSGDLLELA LKLPHVDYIE EDSSVFAQSI PWNLERITPP RYRADEYQPP DGGSLVEVYL LDTSIQSDHR EIEGRVMVTD FENVPEEDGT RFHRQASKCD SHGTHLAGVV SGRDAGVAKG ASMRSLRVLN CQGKGTVSGT LIGLEFIRKS QLVQPVGPLV VLLPLAGGYS RVLNAACQRL ARAGVVLVTA AGNFRDDACL YSPAPAPEVI TVGATNAQDQ PVTLGTLGTN FGRCVDLFAP GEDIIGASSD CSTCFVSQSG TSQAAAHVAG IAAMMLSAEP ELTLAELRQR LIHFSAKDVI NEAWFPEDQR VLTPNLVAAL PPSTHGAGWQ LFCRTVWSAH SGPTRMATAI ARCAPDEELL SCSSFSRSGK RRGERMEAQG GKLVCRAHNA FGGEGVYAIA RCCLLPQANC SVHTAPPAEA SMGTRVHCHQ QGHVLTGCSS HWEVEDLGTH KPPVLRPRGQ PNQCVGHREA SIHASCCHAP GLECKVKEHG IPAPQEQVTV ACEEGWTLTG CSALPGTSHV LGAYAVDNTC VVRSRDVSTT GSTSEEAVTA VAICCRSRHL AQASQELQ
    Characteristics
    Human PCSK9 full-length ORF (no protein_acc, 1 a.a. - 678 a.a.) recombinant protein with GST tag at N-terminal.
    Purification
    in vitro wheat germ expression system
    Top Product
    Discover our top product PCSK9 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Target
    PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
    Alternative Name
    PCSK9 (PCSK9 Products)
    Synonyms
    FH3 Protein, HCHOLA3 Protein, LDLCQ1 Protein, NARC-1 Protein, NARC1 Protein, PC9 Protein, AI415265 Protein, AI747682 Protein, Narc1 Protein, proprotein convertase subtilisin/kexin type 9 Protein, proprotein convertase subtilisin/kexin type 9 L homeolog Protein, PCSK9 Protein, pcsk9.L Protein, pcsk9 Protein, Pcsk9 Protein
    Background
    Synonyms: FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1
    Gene Description: proprotein convertase subtilisin/kexin type 9
    Gene Name: PCSK9
    Gene Summary: This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
    GenBank: AK122717.1
    Molecular Weight
    99.2 kDa (theoreatical)
    Gene ID
    255738
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