BCMA Protein (AA 1-54) (His tag)
Quick Overview for BCMA Protein (AA 1-54) (His tag) (ABIN4949075)
Target
See all BCMA (TNFRSF17) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-54
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Purification tag / Conjugate
- This BCMA protein is labelled with His tag.
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Sequence
- AA 1-54
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Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.5 kDa. the protein migrates as 7-15 kDa under reducing (R) condition, and 15-18 kDa under non-reducing (NR) condition (SDS-PAGE).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Alternative Name
- BCMA
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Background
- Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
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Molecular Weight
- 7.8 kDa
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NCBI Accession
- NP_001183
Target
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