EGFR Protein (Soluble) (Strep Tag)
Quick Overview for EGFR Protein (Soluble) (Strep Tag) (ABIN5564311)
Target
See all EGFR ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Soluble
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Purification tag / Conjugate
- This EGFR protein is labelled with Strep Tag.
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Purpose
- EGFR, Soluble (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Human EGFR (629aa) is fused at the C-terminus to a Strep-tag.
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Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His-Avi Tag)
EGFR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (Biotin,His-Avi Tag)EGFR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (Fc Tag)EGFR Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-378) (Active) protein (His tag,AVI tag,Biotin)EGFR Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (His tag,AVI tag,Biotin)EGFR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His tag)EGFR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, AM, ADA
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (His tag)EGFR Origin: Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Epidermal Growth Factor Receptor (EGFR) (AA 1-405) protein (GST tag)EGFR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Epidermal Growth Factor Receptor (EGFR) (Active) protein (His tag)EGFR Origin: Rat Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Epidermal Growth Factor Receptor (EGFR) (AA 668-1210) (Active) protein (GST tag,His tag)EGFR Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Alternative Name
- EGFR
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Background
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Epidermal Growth Factor Receptor, ERBB1, HER1
EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
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Molecular Weight
- ~85kDa
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UniProt
- P00533
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
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