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Resistin Protein (RETN) (AA 19-108) (DYKDDDDK Tag)

RETN Origin: Human Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN5564365
  • Target See all Resistin (RETN) Proteins
    Resistin (RETN)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 19-108
    Origin
    • 19
    • 8
    • 3
    • 3
    • 1
    Human
    Source
    • 20
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Resistin protein is labelled with DYKDDDDK Tag.
    Application
    SDS-PAGE (SDS)
    Cross-Reactivity
    Human
    Characteristics
    Human resistin (aa 19-108) is fused at the N-terminus to a FLAG®-tag.
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product RETN Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Inhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells.

    Restrictions
    For Research Use only
  • Format
    Solid
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    Resistin (RETN)
    Alternative Name
    Resistin (RETN Products)
    Synonyms
    RETN Protein, ADSF Protein, FIZZ3 Protein, RETN1 Protein, RSTN Protein, XCP1 Protein, Fizz3 Protein, Rstn Protein, Xcp4 Protein, resistin Protein, RETN Protein, Retn Protein
    Background
    The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
    Molecular Weight
    ~13kDa (SDS-PAGE)
    UniProt
    Q9HD89
    Pathways
    Feeding Behaviour, Smooth Muscle Cell Migration
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