AOX1 Protein (AA 236-421, PCMH-type domain) (His tag)
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- Target See all AOX1 Proteins
- AOX1 (Aldehyde Oxidase 1 (AOX1))
- Protein Type
- Recombinant
- Protein Characteristics
- PCMH-type domain, AA 236-421
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AOX1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- FGSERMMWFS PVTLKELLEF KFKYPQAPVI MGNTSVGPEV KFKGVFHPVI ISPDRIEELS VVNHAYNGLT LGAGLSLAQV KDILADVVQK LPEEKTQMYH ALLKHLGTLA GSQIRNMASL GGHIISRHPD SDLNPILAVG NCTLNLLSKE GKRQIPLNEQ FLSKCPNADL KPQEILVSVN IPYSRK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product AOX1 Protein
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Aldehyde Oxidase 1 (AOX1) (AA 1-1338) protein (Strep Tag)
Crystallography grade AOX1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Aldehyde Oxidase 1 (AOX1) (AA 1-1333) protein (Strep Tag)Crystallography grade AOX1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Aldehyde Oxidase 1 (AOX1) protein (Myc-DYKDDDDK Tag)AOX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- AOX1 (Aldehyde Oxidase 1 (AOX1))
- Alternative Name
- AOXA (AOX1 Products)
- Synonyms
- AO Protein, AOH1 Protein, AI196512 Protein, AI255253 Protein, Ao Protein, Aox-1 Protein, Aox-2 Protein, Aox2 Protein, Moro Protein, Ro Protein, aoh1 Protein, AAO1 Protein, ALDEHYDE OXIDASE Protein, AOalpha Protein, ARABIDOPSIS THALIANA ALDEHYDE OXIDASE 1 Protein, AT-AO1 Protein, ATAO Protein, Arabidopsis thaliana aldehyde oxidase 1 Protein, AtAO1 Protein, F22D1.130 Protein, F22D1_130 Protein, aldehyde oxidase 1 Protein, aldehyde oxidase alpha Protein, AOX Protein, Aldox Protein, Ao-1 Protein, Aox Protein, aldox Protein, aldehyde oxidase 1 Protein, aldehyde oxidase 1 L homeolog Protein, Aldehyde oxidase at 89A Protein, hypothetical protein Protein, alternative oxidase Protein, AOX1 Protein, Aox1 Protein, aox1.L Protein, AO1 Protein, Aldox89A Protein, POPTR_0009s15560g Protein
- Background
- Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis
- Molecular Weight
- 24.7 kDa
- UniProt
- Q06278
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