EMID1 Protein (AA 678-751) (His-SUMO Tag)

Catalog No. ABIN5709167

Product Details

Target: EMID1 (EMI Domain Containing 1 (EMID1))

Protein Type: Recombinant

Protein Characteristics: AA 678-751

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EMID1 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: TLQKKIEEIA AKYKHSVVKK CCYDGACVNN DETCEQRAAR ISLGPRCIKA FTECCVVASQ LRANISHKDM QLGR

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: EMID1 (EMI Domain Containing 1 (EMID1))

Alternative Name: CO5 (EMID1 Products)

Synonyms: EMI5 Protein, EMU1 Protein, AW122071 Protein, CO-5 Protein, Emu1 Protein, RGD1565846 Protein, EMI domain containing 1 Protein, EMID1 Protein, Emid1 Protein

Background: Activation of C5 by a C5 convertase initiates the spontaneous assbly of the late complent components, C5-C9, into the mbrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assbled.Derived from proteolytic degradation of complent C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes . C5a is also a potent chokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

Molecular Weight: 24.27 kDa

UniProt: P01031