HAS2 Protein (AA 67-374, Cytoplasmic Domain, Cytosolic) (His tag)
-
- Target See all HAS2 Proteins
- HAS2 (Hyaluronan Synthase 2 (HAS2))
- Protein Type
- Recombinant
- Protein Characteristics
- Cytosolic, AA 67-374, Cytoplasmic Domain
-
Origin
- Mouse
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HAS2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- EHRKMKKSLE TPIKLNKTVA LCIAAYQEDP DYLRKCLQSV KRLTYPGIKV VMVIDGNSDD DLYMMDIFSE VMGRDKSATY IWKNNFHEKG PGETEESHKE SSQHVTQLVL SNKSICIMQK WGGKREVMYT AFRALGRSVD YVQVCDSDTM LDPASSVEMV KVLEEDPMVG GVGGDVQILN KYDSWISFLS SVRYWMAFNI ERACQSYFGC VQCISGPLGM YRNSLLHEFV EDWYNQEFMG NQCSFGDDRH LTNRVLSLGY ATKYTARSKC LTETPIEYLR WLNQQTRWSK SYFREWLYNA MWFHKHHL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HAS2 Protein
-
Hyaluronan Synthase 2 (HAS2) (AA 102-200) protein (GST tag)
HAS2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hyaluronan Synthase 2 (HAS2) (AA 67-374) protein (His tag)Crystallography grade HAS2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Hyaluronan Synthase 2 (HAS2) (AA 67-374) protein (His tag)Crystallography grade HAS2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Hyaluronan Synthase 2 (HAS2) (AA 1-552) protein (Strep Tag)Crystallography grade HAS2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Hyaluronan Synthase 2 (HAS2) (AA 1-552) protein (Strep Tag)Crystallography grade HAS2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Hyaluronan Synthase 2 (HAS2) (AA 67-374), (Cytoplasmic Domain), (Cytosolic) protein (His tag)HAS2 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- HAS2 (Hyaluronan Synthase 2 (HAS2))
- Alternative Name
- HYAS2 (HAS2 Products)
- Synonyms
- DG42 Protein, XHas2 Protein, Has2 Protein, hyaluronan synthase 2 Protein, hyaluronan synthase 2 S homeolog Protein, has2 Protein, HAS2 Protein, Has2 Protein, SHAS2 Protein, has2.S Protein
- Background
- Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.
- Molecular Weight
- 40 kDa
- UniProt
- P70312
- Pathways
- Glycosaminoglycan Metabolic Process
-
