HSD11B1 Protein (AA 25-292) (His-SUMO Tag)
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- Target See all HSD11B1 Proteins
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-292
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HSD11B1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- EEFRPEMLQG KKVIVTGASK GIGREMAYHL AKMGAHVVVT ARSKETLQKV VSHCLELGAA SAHYIAGTME DMTFAEQFVA QAGKLMGGLD MLILNHITNT SLNLFHDDIH HVRKSMEVNF LSYVVLTVAA LPMLKQSNGS IVVVSSLAGK VAYPMVAAYS ASKFALDGFF SSIRKEYSVS RVNVSITLCV LGLIDTETAM KAVSGIVHMQ AAPKEECALE IIKGGALRQE EVYYDSSLWT TLLIRNPCRK ILEFLYSTSY NMDRFINK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HSD11B1 Protein
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Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 196-292) protein (His-IF2DI Tag)
HSD11B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) protein (GST tag)HSD11B1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) protein (His tag)Crystallography grade HSD11B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) protein (His tag)Crystallography grade HSD11B1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 2-292) protein (rho-1D4 tag)Crystallography grade HSD11B1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 2-292) protein (rho-1D4 tag)Crystallography grade HSD11B1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HSD11B1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- Alternative Name
- DHI1 (HSD11B1 Products)
- Synonyms
- 11-DH Protein, 11-beta-HSD1 Protein, CORTRD2 Protein, HDL Protein, HSD11 Protein, HSD11B Protein, HSD11L Protein, SDR26C1 Protein, hsd11 Protein, hsd11b Protein, LRRGT00065 Protein, hydroxysteroid 11-beta dehydrogenase 1 Protein, hydroxysteroid (11-beta) dehydrogenase 1b Protein, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog Protein, HSD11B1 Protein, HSD11B1b Protein, hsd11b1.L Protein, Hsd11b1 Protein
- Background
- Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol .
- Molecular Weight
- 45.5 kDa
- UniProt
- P28845
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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