NANOS2 Protein (AA 1-138, full length) (His-SUMO Tag)
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- Target See all NANOS2 Proteins
- NANOS2 (Nanos Homolog 2 (NANOS2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-138, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NANOS2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MQLPPFDMWK DYFNLSQVVW ALIASRGQRL ETQEIEEPSP GPPLGQDQGL GAPGANGGLG TLCNFCKHNG ESRHVYSSHQ LKTPDGVVVC PILRHYVCPV CGATGDQAHT LKYCPLNGGQ QSLYRRSGRN SAGRRVKR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NANOS2 Protein
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Nanos Homolog 2 (NANOS2) (AA 97-173) protein (GST tag)
NANOS2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nanos Homolog 2 (NANOS2) (AA 1-138) protein (Strep Tag)Crystallography grade NANOS2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Nanos Homolog 2 (NANOS2) (AA 1-136) protein (Strep Tag)Crystallography grade NANOS2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Nanos Homolog 2 (NANOS2) protein (Myc-DYKDDDDK Tag)NANOS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NANOS2 (Nanos Homolog 2 (NANOS2))
- Alternative Name
- NANO2 (NANOS2 Products)
- Synonyms
- NOS2 Protein, RGD1562436 Protein, nos2 Protein, nanos C2HC-type zinc finger 2 Protein, nanos homolog 2 (Drosophila) Protein, nanos 2 Protein, nanos2 protein Protein, NANOS2 Protein, Nanos2 Protein, nanos2 Protein
- Background
- Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the fale fate. Represses the fale fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for preiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial st cell population. Not essential for the assbly of P-bodies but is required for the maintenance of their normal state .
- Molecular Weight
- 31.1 kDa
- UniProt
- P60321
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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