NDST1 Protein (AA 40-556, Isoform 2) (His-SUMO Tag)
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- Target See all NDST1 Proteins
- NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 40-556, Isoform 2
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NDST1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GWKRGLEPSA DAPEPDCGDP PPVAPSRLLP LKPVQAATPS RTDPLVLVFV ESLYSQLGQE VVAILESSRF KYRTEIAPGK GDMPTLTDKG RGRFALIIYE NILKYVNLDA WNRELLDKYC VAYGVGIIGF FKANENSLLS AQLKGFPLFL HSNLGLKDCS INPKSPLLYV TRPSEVEKGV LPGEDWTVFQ SNHSTYEPVL LAKTRSSESI PHLGADAGLH AALHATVVQD LGLHDGIQRV LFGNNLNFWL HKLVFVDAVA FLTGKRLSLP LDRYILVDID DIFVGKEGTR MKVEDVKALF DTQNELRAHI PNFTFNLGYS GKFFQTGTNA EDAGDDLLLS YVKEFWWFPH MWSHMQPHLF HNQSVLAEQM ALNKKFAVEH GIPTDMGYAV APHHSGVYPV HVQLYEAWKQ VWSIRVTSTE EYPHLKPARY RRGFIHNGIM VLPRQTCGLF THTIFYNEYP GGSSELDKII NGGELFLTVL LNPVSAPQPM AAGEKGLLHS LSAADTGFLE PGKGGEA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NDST1 Protein
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N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 38-136) protein (GST tag)
NDST1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 1-882) protein (GST tag)NDST1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 1-882) protein (Strep Tag)Crystallography grade NDST1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 1-882) protein (Strep Tag)Crystallography grade NDST1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 40-882) protein (His tag)Crystallography grade NDST1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) (AA 39-882) protein (His tag)Crystallography grade NDST1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) protein (Myc-DYKDDDDK Tag)NDST1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
- Alternative Name
- NDST1 (NDST1 Products)
- Synonyms
- HSST Protein, NST1 Protein, 1200015G06Rik Protein, Hsst Protein, NDST-1 Protein, fj47c03 Protein, ndst1 Protein, wu:fj47c03 Protein, NDST1 Protein, N-deacetylase and N-sulfotransferase 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog Protein, NDST1 Protein, Ndst1 Protein, ndst1b Protein, ndst1 Protein, ndst1.S Protein
- Background
- Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
- Molecular Weight
- 73.5 kDa
- UniProt
- P52848
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process
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