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REG3g Protein (AA 27-174) (His tag)

REG3g Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710242
  • Target See all REG3g Proteins
    REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-174
    Origin
    • 11
    • 5
    • 3
    Rat
    Source
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This REG3g protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    EDAKEDVPTS RISCPKGSRA YGSYCYALFS VSKSWFDADL ACQKRPSGHL VSVLSGSEAS FVSSLIKSSG NSGQNVWIGL HDPTLGQEPN RGGWEWSNAD VMNYFNWETN PSSVSGSHCG TLTRASGFLR WRENNCISEL PYVCKFKA
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product REG3g Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))
    Alternative Name
    REG3G (REG3g Products)
    Synonyms
    LPPM429 Protein, PAP IB Protein, PAP-1B Protein, PAP1B Protein, PAPIB Protein, REG III Protein, REG-III Protein, UNQ429 Protein, AI449515 Protein, PAPIII Protein, Pap3 Protein, REG3A Protein, regenerating family member 3 gamma Protein, regenerating islet-derived 3 gamma Protein, REG3G Protein, Reg3g Protein
    Background
    Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury .
    Molecular Weight
    20.34 kDa
    UniProt
    P42854
    Pathways
    Activation of Innate immune Response
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