NR1H3 Protein (AA 1-402, Isoform 3) (His-SUMO Tag)
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- Target See all NR1H3 Proteins
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Protein Type
- Recombinant
- Protein Characteristics
- Isoform 3, AA 1-402
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NR1H3 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MPHSAGGTAG VGLEAAEPTA LLTRAEPPSE PTEIRPQKRK KGPAPKMLGN ELCSVCGDKA SGFHYNVLSC EGCKGFFRRS VIKGAHYICH SGGHCPMDTY MRRKCQECRL RKCRQAGMRE ECVLSEEQIR LKKLKRQEEE QAHATSLPPR ASSPPQILPQ LSPEQLGMIE KLVAAQQQCN RRSFSDRLRV TPWPMAPDPH SREARQQRFA HFTELAIVSV QEIVDFAKQL PGFLQLSRED QIALLKTSAI EVMLLETSRR YNPGSESITF LKDFSYNRED FAKAGLQVEF INPIFEFSRA MNELQLNDAE FALLIAISIF SADRPNVQDQ LQVERLQHTY VEALHAYVSI HHPHDRLMFP RMLMKLVSLR TLSSVHSEQV FALRLQDKKL PPLLSEIWDV HE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NR1H3 Protein
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Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-387) protein (GST tag)
NR1H3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-447) protein (Strep Tag)Crystallography grade NR1H3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-445) protein (Strep Tag)Crystallography grade NR1H3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NR1H3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Alternative Name
- NR1H3 (NR1H3 Products)
- Synonyms
- NR1H3 Protein, LXR-a Protein, LXRA Protein, RLD-1 Protein, AU018371 Protein, LXR Protein, RLD1 Protein, Unr1 Protein, LXRalpha Protein, LXR-alpha Protein, im:7141239 Protein, wu:fd59b01 Protein, zgc:113339 Protein, zgc:158542 Protein, nuclear receptor subfamily 1 group H member 3 Protein, nuclear receptor subfamily 1, group H, member 3 Protein, NR1H3 Protein, nr1h3 Protein, Nr1h3 Protein
- Background
- Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elents characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism .
- Molecular Weight
- 61.7 kDa
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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