NET1 Protein (AA 1-542, Isoform 2) (His-SUMO Tag)
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- Target See all NET1 Proteins
- NET1 (Neuroepithelial Cell Transforming 1 (NET1))
- Protein Type
- Recombinant
- Protein Characteristics
- Isoform 2, AA 1-542
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NET1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MVAHDETGGL LPIKRTIRVL DVNNQSFREQ EEPSNKRVRP LARVTSLANL ISPVRNGAVR RFGQTIQSFT LRGDHRSPAS AQKFSSRSTV PTPAKRRSSA LWSEMLDITM KESLTTREIR RQEAIYEMSR GEQDLIEDLK LARKAYHDPM LKLSIMSEEE LTHIFGDLDS YIPLHEDLLT RIGEATKPDG TVEQIGHILV SWLPRLNAYR GYCSNQLAAK ALLDQKKQDP RVQDFLQRCL ESPFSRKLDL WSFLDIPRSR LVKYPLLLKE ILKHTPKEHP DVQLLEDAIL IIQGVLSDIN LKKGESECQY YIDKLEYLDE KQRDPRIEAS KVLLCHGELR SKSGHKLYIF LFQDILVLTR PVTRNERHSY QVYRQPIPVQ ELVLEDLQDG DVRMGGSFRG AFSNSEKAKN IFRIRFHDPS PAQSHTLQAN DVFHKQQWFN CIRAAIAPFQ SAGSPPELQG LPELHEECEG NHPSARKLTA QRRASTVSSV TQVEVDENAY RCGSGMQMAE DSKSLKTHQT QPGIRRARDK ALSGGKRKET LV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NET1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NET1 (Neuroepithelial Cell Transforming 1 (NET1))
- Alternative Name
- ARHG8 (NET1 Products)
- Synonyms
- arhgef8 Protein, net1a Protein, xNET1 Protein, DKFZp459I0423 Protein, NET1 Protein, ARHGEF8 Protein, NET1A Protein, 0610025H04Rik Protein, 9530071N24Rik Protein, AI604373 Protein, AU015857 Protein, Net1a Protein, mNET1 Protein, wu:fb13g03 Protein, wu:fb25c11 Protein, zgc:92121 Protein, neuroepithelial cell transforming 1 Protein, neuroepithelial cell-transforming gene 1 protein Protein, neuroepithelial cell transforming 1 L homeolog Protein, neuroepithelial cell transforming gene 1 Protein, net1 Protein, EDI_348570 Protein, NET1 Protein, Net1 Protein, net1.L Protein
- Background
- Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
- Molecular Weight
- 77.8 kDa
- UniProt
- Q7Z628
- Pathways
- Neurotrophin Signaling Pathway
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