AEN Protein (AA 117-325, partial) (His-SUMO Tag)
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- Target See all AEN Proteins
- AEN (Apoptosis Enhancing Nuclease (AEN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 117-325, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AEN protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MVGTGPRGRV SELARCSIVS YHGDVLYDKY IRPEMPIADY RTRWSGITRQ HMRKAVPFQV AQKEILKLLK GKVVVGHALH NDFQALKYVH PRSQTRDTTY VPNFLSEPGL HTRARVSLKD LALQLLHKKI QVGQHGHSSV EDATTAMELY RLVEVQWEQQ EARSLWTCPE DREPDSSTDM EQYMEDQYWP DDLAHGSRGG AREAQDRRN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product AEN Protein
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Apoptosis Enhancing Nuclease (AEN) (AA 1-325) protein (Strep Tag)
Crystallography grade AEN Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Apoptosis Enhancing Nuclease (AEN) (AA 1-336) protein (Strep Tag)Crystallography grade AEN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- AEN (Apoptosis Enhancing Nuclease (AEN))
- Alternative Name
- AEN (AEN Products)
- Synonyms
- AEN Protein, ISG20L1 Protein, xaen Protein, isg20l1 Protein, MGC147218 Protein, pp12744 Protein, 2700083B06Rik Protein, Isg20l1 Protein, RGD1305051 Protein, apoptosis enhancing nuclease Protein, apoptosis enhancing nuclease L homeolog Protein, AEN Protein, aen.L Protein, aen Protein, Aen Protein
- Background
- Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancent of apoptosis.
- Molecular Weight
- 40.08 kDa
- UniProt
- Q8WTP8
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