NMNAT3 Protein (AA 1-215, Isoform 2) (His-SUMO Tag)
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- Target See all NMNAT3 Proteins
- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-215, Isoform 2
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NMNAT3 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MYQVIQGIIS PVNDTYGKKD LAASHHRVAM ARLALQTSDW IRVDPWESEQ AQWMETVKVL RHHHSKLLRS PPQMEGPDHG KALFSTPAAV PELKLLCGAD VLKTFQTPNL WKDAHIQEIV EKFGLVCVGR VGHDPKGYIA ESPILRMHQH NIHLAKEPVQ NEISATYIRR ALGQGQSVKY LIPDAVITYI KDHGLYTKGS TWKGKSTQST EGKTS
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NMNAT3 Protein
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Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-252) protein (His tag)
NMNAT3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-215) protein (GST tag)NMNAT3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 116-215) protein (GST tag)NMNAT3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-245) protein (Strep Tag)Crystallography grade NMNAT3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
- Alternative Name
- NMNA3 (NMNAT3 Products)
- Synonyms
- PNAT-3 Protein, PNAT3 Protein, 4933408N02Rik Protein, nicotinamide nucleotide adenylyltransferase 3 Protein, si:ch73-170l17.1 Protein, Nmnat3 Protein, NMNAT3 Protein, si:ch73-170l17.1 Protein
- Background
- Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, can use NAD+, NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NaADP+. Protects against axonal degeneration following injury.
- Molecular Weight
- 40.1 kDa
- UniProt
- Q96T66
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