OBFC2A Protein (AA 1-204, full length) (His-SUMO Tag)
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- Target See all OBFC2A Proteins
- OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-204, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This OBFC2A protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MNRVNDPLIF IRDIKPGLKN LNVVFIVLEI GRVTKTKDGH EVRSCKVADK TGSITISVWD EIGGLIQPGD IIRLTRGYAS MWKGCLTLYT GRGGELQKIG EFCMVYSEVP NFSEPNPDYR GQQNKGAQSE QKNNSMNSNM GTGTFGPVGN GVHTGPESRE HQFSHAGRSN GRGLINPQLQ GTASNQTVMT TISNGRDPRR AFKR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product OBFC2A Protein
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Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-204) protein (GST tag)
OBFC2A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-204) protein (Strep Tag)Crystallography grade OBFC2A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A) (AA 1-198) protein (Strep Tag)Crystallography grade OBFC2A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
- Alternative Name
- SOSB2 (OBFC2A Products)
- Synonyms
- OBFC2A Protein, SOSS-B2 Protein, SSB2 Protein, 4930434H03Rik Protein, 4930442A21Rik Protein, 4930488J04Rik Protein, 4933440J18Rik Protein, 5830411E10Rik Protein, AI852561 Protein, Nbp1 Protein, Obfc2a Protein, Ssb2 Protein, RGD1306658 Protein, nucleic acid binding protein 1 Protein, NABP1 Protein, Nabp1 Protein
- Background
- Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
- Molecular Weight
- 38.4 kDa
- UniProt
- Q96AH0
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