GEMIN7 Protein (AA 1-131, full length) (GST tag)
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- Target See all GEMIN7 Proteins
- GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-131
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GEMIN7 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MQTPVNIPVP VLRLPRGPDG FSRGFAPDGR RAPLRPEVPE IQECPIAQES LESQEQRARA ALRERYLRSL LAMVGHQVSF TLHEGVRVAA HFGATDLDVA NFYVSQLQTP IGVQAEALLR CSDIISYTFK P
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GEMIN7 Protein
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Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7) (AA 1-131) protein (GST tag)
GEMIN7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7) (AA 43-131) protein (GST tag)GEMIN7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7) (AA 1-131) protein (Strep Tag)Crystallography grade GEMIN7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7) (AA 1-129) protein (Strep Tag)Crystallography grade GEMIN7 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7) protein (His tag)GEMIN7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
- Alternative Name
- GEMI7 (GEMIN7 Products)
- Synonyms
- SIP3 Protein, GEMIN7 Protein, Gemin7 Protein, 2400008I04Rik Protein, AI120175 Protein, AI461688 Protein, gem nuclear organelle associated protein 7 Protein, gem (nuclear organelle) associated protein 7 Protein, GEMIN7 Protein, Gemin7 Protein
- Background
- The SMN complex plays a catalyst role in the assbly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assbly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assbly of core snRNPs and their transport to the nucleus.
- Molecular Weight
- 41.9 kDa
- UniProt
- Q9H840
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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