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TRAP1 Protein (AA 60-308, partial) (GST tag)

TRAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4976541
  • Target See all TRAP1 Proteins
    TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 60-308, partial
    Origin
    • 4
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TRAP1 protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    STQTAEDKEE PLHSIISSTE SVQGSTSKHE FQAETKKLLD IVARSLYSEK EVFIRELISN ASDALEKLRH KLVSDGQALP EMEIHLQTNA EKGTITIQDT GIGMTQEELV SNLGTIARSG SKAFLDALQN QAEASSKIIG QFGVGFYSAF MVADRVEVYS RSAAPGSLGY QWLSDGSGVF EIAEASGVRT GTKIIIHLKS DCKEFSSEAR VRDVVTKYSN FVSFPLYLNG RRMNTLQAIW MMDPKDVRE
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product TRAP1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
    Alternative Name
    TRAP1 (TRAP1 Products)
    Synonyms
    HSP 75 Protein, HSP75 Protein, HSP90L Protein, TRAP-1 Protein, 2410002K23Rik Protein, fc85a11 Protein, wu:fc85a11 Protein, TNF receptor associated protein 1 Protein, TNF receptor-associated protein 1 Protein, TRAP1 Protein, Trap1 Protein, trap1 Protein
    Background
    Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
    Molecular Weight
    54.8 kDa
    UniProt
    Q12931
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