TRAP1 Protein (AA 60-308, partial) (GST tag)
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- Target See all TRAP1 Proteins
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 60-308, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TRAP1 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- STQTAEDKEE PLHSIISSTE SVQGSTSKHE FQAETKKLLD IVARSLYSEK EVFIRELISN ASDALEKLRH KLVSDGQALP EMEIHLQTNA EKGTITIQDT GIGMTQEELV SNLGTIARSG SKAFLDALQN QAEASSKIIG QFGVGFYSAF MVADRVEVYS RSAAPGSLGY QWLSDGSGVF EIAEASGVRT GTKIIIHLKS DCKEFSSEAR VRDVVTKYSN FVSFPLYLNG RRMNTLQAIW MMDPKDVRE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TRAP1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Alternative Name
- TRAP1 (TRAP1 Products)
- Synonyms
- HSP 75 Protein, HSP75 Protein, HSP90L Protein, TRAP-1 Protein, 2410002K23Rik Protein, fc85a11 Protein, wu:fc85a11 Protein, TNF receptor associated protein 1 Protein, TNF receptor-associated protein 1 Protein, TRAP1 Protein, Trap1 Protein, trap1 Protein
- Background
- Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
- Molecular Weight
- 54.8 kDa
- UniProt
- Q12931
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