GPR161 Protein (AA 1-28, Extracellular, partial) (GST tag)
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- Target See all GPR161 Proteins
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 1-28, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GPR161 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSLNSSLSCR KELSNLTEEE GGEGGVII
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GPR161 Protein
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G Protein-Coupled Receptor 161 (GPR161) (AA 362-460) protein (GST tag)
GPR161 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
G Protein-Coupled Receptor 161 (GPR161) (AA 328-529) protein (His tag)Crystallography grade GPR161 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
G Protein-Coupled Receptor 161 (GPR161) (AA 344-545) protein (His tag)Crystallography grade GPR161 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
G Protein-Coupled Receptor 161 (GPR161) (AA 1-529) protein (Strep Tag)Crystallography grade GPR161 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
G Protein-Coupled Receptor 161 (GPR161) (AA 1-545) protein (Strep Tag)Crystallography grade GPR161 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
G Protein-Coupled Receptor 161 (GPR161) (AA 1-28), (partial) protein (GST tag)GPR161 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Alternative Name
- GP161 (GPR161 Products)
- Synonyms
- RE2 Protein, Gm208 Protein, Gm208Gpr Protein, vl Protein, RGD1563245 Protein, si:bz20i5.4 Protein, si:rp71-20i5.4 Protein, G protein-coupled receptor 161 Protein, GPR161 Protein, Gpr161 Protein, gpr161 Protein
- Background
- Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is roved from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown .
- Molecular Weight
- 30.4 kDa
- UniProt
- Q8N6U8
- Pathways
- cAMP Metabolic Process
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