MAP2 Protein (AA 2-478) (His tag)
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- Target See all MAP2 Proteins
- MAP2 (Microtubule-Associated Protein 2 (MAP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-478
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This MAP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AGVEEVAASG SHLNGDLDPD DREEGAASTA EEAAKKKRRK KKKSKGPSAA GEQEPDKESG ASVDEVARQL ERSALEDKER DEDDEDGDGD GDGATGKKKK KKKKKRGPKV QTDPPSVPIC DLYPNGVFPK GQECEYPPTQ DGRTAAWRTT SEEKKALDQA SEEIWNDFRE AAEAHRQVRK YVMSWIKPGM TMIEICEKLE DCSRKLIKEN GLNAGLAFPT GCSLNNCAAH YTPNAGDTTV LQYDDICKID FGTHISGRII DCAFTVTFNP KYDTLLKAVK DATNTGIKCA GIDVRLCDVG EAIQEVMESY EVEIDGKTYQ VKPIRNLNGH SIGQYRIHAG KTVPIVKGGE ATRMEEGEVY AIETFGSTGK GVVHDDMECS HYMKNFDVGH VPIRLPRTKH LLNVINENFG TLAFCRRWLD RLGESKYLMA LKNLCDLGIV DPYPPLCDIK GSYTAQFEHT ILLRPTCKEV VSRGDDY
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MAP2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MAP2 (Microtubule-Associated Protein 2 (MAP2))
- Alternative Name
- MAP2 (MAP2 Products)
- Synonyms
- MAP2A Protein, MAP2B Protein, MAP2C Protein, MAP2R Protein, Mtap2 Protein, MAP-2 Protein, Mtap-2 Protein, xmap2 Protein, MGC53131 Protein, a730034c02 Protein, zgc:103474 Protein, zgc:113974 Protein, microtubule associated protein 2 Protein, microtubule-associated protein 2 Protein, microtubule associated protein 2 S homeolog Protein, MAP2 Protein, Map2 Protein, map2.S Protein, map2 Protein
- Background
- Cotranslationally roves the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
- Molecular Weight
- 54.7 kDa
- UniProt
- P50579
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