C22orf28 Protein (AA 1-408, full length) (His tag)
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- Target See all C22orf28 Proteins
- C22orf28 (Chromosome 22 Open Reading Frame 28 (C22orf28))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-408, full length
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Origin
- E. coli
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Source
- Yeast
- Purification tag / Conjugate
- This C22orf28 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- NYELLTTENA PVKMWTKGVP VEADARQQLI NTAKMPFIFK HIAVMPDVHL GKGSTIGSVI PTKGAIIPAA VGVDIGCGMN ALRTALTAED LPENLAELRQ AIETAVPHGR TTGRCKRDKG AWENPPVNVD AKWAELEAGY QWLTQKYPRF LNTNNYKHLG TLGTGNHFIE ICLDESDQVW IMLHSGSRGI GNAIGTYFID LAQKEMQETL ETLPSRDLAY FMEGTEYFDD YLKAVAWAQL FASLNRDAMM ENVVTALQSI TQKTVRQPQT LAMEEINCHH NYVQKEQHFG EEIYVTRKGA VSARAGQYGI IPGSMGAKSF IVRGLGNEES FCSCSHGAGR VMSRTKAKKL FSVEDQIRAT AHVECRKDAE VIDEIPMAYK DIDAVMAAQS DLVEVIYTLR QVVCVKG
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product C22orf28 Protein
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Chromosome 22 Open Reading Frame 28 (C22orf28) (AA 1-505) protein (GST tag)
C22orf28 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chromosome 22 Open Reading Frame 28 (C22orf28) (AA 1-505) protein (Strep Tag)Crystallography grade C22orf28 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Chromosome 22 Open Reading Frame 28 (C22orf28) (AA 1-505) protein (Strep Tag)Crystallography grade C22orf28 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Chromosome 22 Open Reading Frame 28 (C22orf28) protein (Myc-DYKDDDDK Tag)C22orf28 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- C22orf28 (Chromosome 22 Open Reading Frame 28 (C22orf28))
- Alternative Name
- RTCB (C22orf28 Products)
- Synonyms
- C1H22orf28 Protein, C22orf28 Protein, DJ149A16.6 Protein, FAAP Protein, RP1-149A16.6 Protein, c22orf28 Protein, C10H22orf28 Protein, MGC154502 Protein, HSPC117 Protein, AI255213 Protein, AI463255 Protein, RNA 2',3'-cyclic phosphate and 5'-OH ligase Protein, tRNA-splicing ligase RtcB homolog Protein, RTCB Protein, rtcb Protein, rtcb.L Protein, Rtcb Protein
- Background
- RNA ligase that mediates the joining of broken tRNA-like st-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like st-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester, a step that requires GTP . Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-PO4 (or cyclic-PO4) and 5'-OH ends that cannot be sealed by classical DNA ligases .
- Molecular Weight
- 47.1 kDa
- UniProt
- P46850
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