GREM2 Protein (AA 22-168) (His tag)
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- Target See all GREM2 Proteins
- GREM2 (Gremlin 2 (GREM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-168
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GREM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSRKNRPAG AIPSPYKDGS SNNSERWQHQ IKEVLASSQE ALVVTERKYL KSDWCKTQPL RQTVSEEGCR SRTILNRFCY GQCNSFYIPR HVKKEEESFQ SCAFCKPQRV TSVLVELECP GLDPPFRLKK IQKVKQCRCM SVNLSDSDKQ
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product GREM2 Protein
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Gremlin 2 (GREM2) (AA 1-168) protein (GST tag)
GREM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Gremlin 2 (GREM2) (AA 22-168) protein (His tag)Crystallography grade GREM2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Gremlin 2 (GREM2) (AA 22-168) protein (His tag)Crystallography grade GREM2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GREM2 (Gremlin 2 (GREM2))
- Alternative Name
- GREM2 (GREM2 Products)
- Synonyms
- prdc Protein, zgc:112207 Protein, RGD1560008 Protein, Gremlin2 Protein, Prdc Protein, CKTSF1B2 Protein, DAND3 Protein, PRDC Protein, gremlin 2, DAN family BMP antagonist Protein, gremlin 2, DAN family BMP antagonist b Protein, gremlin 2, cysteine knot superfamily Protein, GREM2 Protein, grem2b Protein, grem2 Protein, Grem2 Protein
- Background
- GREM2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. Recombinant human GREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 19 kDa (170aa)
- NCBI Accession
- NP_071914
- UniProt
- Q9H772
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