ZFAND1 Protein (AA 1-268) (His tag)

Catalog No. ABIN5852954

Product Details

Target: ZFAND1 (Zinc Finger, AN1-Type Domain 1 (ZFAND1))

Protein Type: Recombinant

Protein Characteristics: AA 1-268

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ZFAND1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAELDIG QHCQVEHCRQ RDFLPFVCDD CSGIFCLEHR SRESHGCPEV TVINERLKTD QHTSYPCSFK DCAERELVAV ICPYCEKNFC LRHRHQSDHE CEKLEIPKPR MAATQKLVKD IIDSKTGETA SKRWKGAKNS ETAAKVALMK LKMHADGDKS LPQTERIYFQ VFLPKGSKEK SKPMFFCHRW SIGKAIDFAA SLARLKNDNN KFTAKKLRLC HITSGEALPL DHTLETWIAK EDCPLYNGGN IILEYLNDEE QFCKNVESYL E

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: ZFAND1 (Zinc Finger, AN1-Type Domain 1 (ZFAND1))

Alternative Name: ZFAND1 (ZFAND1 Products)

Synonyms: RGD1309519 Protein, zgc:100786 Protein, ZFAND1 Protein, IMPA1 Protein, 2310008M20Rik Protein, AW048890 Protein, zinc finger AN1-type containing 1 Protein, zinc finger, AN1-type domain 1 Protein, Zfand1 Protein, ZFAND1 Protein, zfand1 Protein

Background: AN1-type zinc finger protein 1 isoform a, also known as ZFAND1, belongs to the Zinc-finger proteins. Zinc -finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZFAND1 is a 268 amino acid protein that contains 2 AN1-type zinc fingers, which are often found in proteins that contain an ubiquitin-like domain and therefore play a role in the ubiquitination pathway. ZFAND1 contains six conserved cysteines and two histidines and have a dimetal (zinc)-bound alpha/beta fold. There are two isoforms of ZFAND1 that are produced as a result of alternative splicing events. Recombinant human ZFAND1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 33.2kDa (291aa) confirmed by MALDI-TOF

NCBI Accession: NP_078975

UniProt: Q8TCF1