FIBP Protein (AA 1-364) (His tag)

Catalog No. ABIN5853020

Product Details

Target: FIBP (Fibroblast Growth Factor (Acidic) Intracellular Binding Protein (FIBP))

Protein Type: Recombinant

Protein Characteristics: AA 1-364

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FIBP protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTSELDI FVGNTTLIDE DVYRLWLDGY SVTDAVALRV RSGILEQTGA TAAVLQSDTM DHYRTFHMLE RLLHAPPKLL HQLIFQIPPS RQALLIERYY AFDEAFVREV LGKKLSKGTK KDLDDISTKT GITLKSCRRQ FDNFKRVFKV VEEMRGSLVD NIQQHFLLSD RLARDYAAIV FFANNRFETG KKKLQYLSFG DFAFCAELMI QNWTLGAVGE APTDPDSQMD DMDMDLDKEF LQDLKELKVL VADKDLLDLH KSLVCTALRG KLGVFSEMEA NFKNLSRGLV NVAAKLTHNK DVRDLFVDLV EKFVEPCRSD HWPLSDVRFF LNQYSASVHS LDGFRHQALW DRYMGTLRGC LLRLYHD

Purity: > 95 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: FIBP (Fibroblast Growth Factor (Acidic) Intracellular Binding Protein (FIBP))

Alternative Name: FIBP (FIBP Products)

Synonyms: 2010004G08Rik Protein, 2010005N21Rik Protein, 3010027N18Rik Protein, FGFIBP Protein, FIBP-1 Protein, fibp Protein, zgc:64086 Protein, aFGF intracellular-binding protein B Protein, fibpl Protein, zgc:103503 Protein, fibroblast growth factor (acidic) intracellular binding protein Protein, FGF1 intracellular binding protein Protein, fibroblast growth factor (acidic) intracellular binding protein a Protein, fibroblast growth factor (acidic) intracellular binding protein L homeolog Protein, fibroblast growth factor (acidic) intracellular binding protein b Protein, Fibp Protein, FIBP Protein, fibpa Protein, fibp.L Protein, fibpb Protein

Background: Acidic fibroblast growth factor intracellular-binding protein isoform a, also known as FIBP, is a member of Fibroblast growth factors (FGFs) represent a family. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer progression. FIBP is a 364 amino acid protein that binds to internalized FGF-1 and is thought to be involved in mitogenic function of FGF-1. FIBP localizes to the nucleus and is highly expressed in heart, skeletal muscle and pancreas and at lower levels in brain, placenta, liver and kidney. Recombinant human FIBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 44.3kDa (387aa), confirmed by MALDI-TOF

NCBI Accession: NP_942600

UniProt: O43427