TNFAIP8 Protein (AA 1-198) (His tag)
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- Target See all TNFAIP8 Proteins
- TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TNFAIP8 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMHSEAEE SKEVATDVFN SKNLAVQAQK KILGKMVSKS IATTLIDDTS SEVLDELYRV TREYTQNKKE AEKIIKNLIK TVIKLAILYR NNQFNQDELA LMEKFKKKVH QLAMTVVSFH QVDYTFDRNV LSRLLNECRE MLHQIIQRHL TAKSHGRVNN VFDHFSDCEF LAALYNPFGN FKPHLQKLCD GINKMLDEEN I
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TNFAIP8 Protein
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Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (AA 1-198) protein (GST tag)
TNFAIP8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (AA 1-198) protein (Strep Tag)Crystallography grade TNFAIP8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (AA 2-198), (full length) protein (GST tag)TNFAIP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TNFAIP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TNFAIP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))
- Alternative Name
- TNFAIP8 (TNFAIP8 Products)
- Synonyms
- MGC55331 Protein, zgc:55331 Protein, si:dkey-49m19.6 Protein, GG2-1 Protein, MDC-3.13 Protein, SCC-S2 Protein, SCCS2 Protein, AA987150 Protein, E130304C20Rik Protein, ENSMUSG00000073567 Protein, Gg2-1 Protein, Gm10539 Protein, Nded Protein, Ssc-2 Protein, tumor necrosis factor, alpha-induced protein 8-like 1 Protein, TNF alpha induced protein 8 S homeolog Protein, TNF alpha induced protein 8 Protein, tumor necrosis factor, alpha-induced protein 8 Protein, tnfaip8l1 Protein, tnfaip8.S Protein, TNFAIP8 Protein, Tnfaip8 Protein
- Background
- TNFAIP8 belongs to the TNFAIP8 family. This protein acts as a negative mediator of apoptosis and may play a role in tumor progression. It suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Recombinant human TNFAIP8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25kDa (221aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_055165
- UniProt
- O95379
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