MPZL1 Protein (AA 38-162) (His tag)
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- Target See all MPZL1 Proteins
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 38-162
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MPZL1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSLEVYTPK EIFVANGTQG KLTCKFKSTS TTGGLTSVSW SFQPEGADTT VSFFHYSQGQ VYLGNYPPFK DRISWAGDLD KKDASINIEN MQFIHNGTYI CDVKNPPDIV VQPGHIRLYV VEKENLPV
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MPZL1 Protein
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Myelin Protein Zero-Like 1 (MPZL1) (AA 1-269) protein (GST tag)
MPZL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Myelin Protein Zero-Like 1 (MPZL1) (AA 36-162) protein (His tag)Crystallography grade MPZL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Myelin Protein Zero-Like 1 (MPZL1) (AA 36-162) protein (His tag)Crystallography grade MPZL1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Myelin Protein Zero-Like 1 (MPZL1) (AA 36-269) protein (rho-1D4 tag)Crystallography grade MPZL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Myelin Protein Zero-Like 1 (MPZL1) (AA 36-270) protein (rho-1D4 tag)Crystallography grade MPZL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Myelin Protein Zero-Like 1 (MPZL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MPZL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- Alternative Name
- MPZL1 (MPZL1 Products)
- Synonyms
- MPZL1 Protein, MPZL1b Protein, PZR Protein, PZR1b Protein, PZRa Protein, PZRb Protein, 1110007A10Rik Protein, myelin protein zero like 1 Protein, myelin protein zero-like 1 Protein, MPZL1 Protein, Mpzl1 Protein
- Background
- MPZL1 is a cell surface receptor, which is involved in signal transduction processes. This protein recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. Recombinant human MPZL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 16.1 kDa (148aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_078845
- UniProt
- O95297
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