NEURL2 Protein (AA 1-285) (His tag)
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- Target See all NEURL2 Proteins
- NEURL2 (Neuralized Homolog 2 (NEURL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-285
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NEURL2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAAASEP VDSGALWGLE RPEPPPTRFH RVHGANIRVD PSGTRATRVE SFAHGVCFSR EPLAPGQVFL VEIEEKELGW CGHLRLGLTA LDPASLAPVP EFSLPDLVNL GHTWVFAITR HHNRVPREGR PEAEAAAPSR PPTLLVEPYL RIEQFRIPRD RLVGRSRPGL YSHLLDQLYE LNVLPPTARR SRLGVLFCPR PDGTADMHII INGEDMGPSA RGLPAAQPLY AVVDVFASTK SVRLVQLEYG LPSLQTLCRL VIQRSMVHRL AIDGLHLPKE LKDFCKYE
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NEURL2 Protein
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Neuralized Homolog 2 (NEURL2) (AA 1-285) protein (Strep Tag)
Crystallography grade NEURL2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Neuralized Homolog 2 (NEURL2) (AA 1-285) protein (Strep Tag)Crystallography grade NEURL2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Neuralized Homolog 2 (NEURL2) protein (Myc-DYKDDDDK Tag)NEURL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- NEURL2 (Neuralized Homolog 2 (NEURL2))
- Alternative Name
- NEuRL2 (NEURL2 Products)
- Synonyms
- C20orf163 Protein, OZZ Protein, OZZ-E3 Protein, Neur2 Protein, Ozz Protein, Ozz-E3 Protein, neuralized E3 ubiquitin protein ligase 2 Protein, NEURL2 Protein, Neurl2 Protein
- Background
- NEuRL2 plays an important role in the process of myofiber differentiation and maturation. This protein is probable substrate-recognition component of a SCF-like ECS (Elongin BC-CuL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. It probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, NEuRL2 controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma. Recombinant human NEuRL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 34.1kDa (308aa)
- NCBI Accession
- NP_542787
- UniProt
- Q9BR09
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