TIPIN Protein (AA 1-301) (His tag)
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- Target See all TIPIN Proteins
- TIPIN (TIMELESS Interacting Protein (TIPIN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-301
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TIPIN protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMLEPQEN GVIDLPDYEH VEDETFPPFP PPASPERQDG EGTEPDEESG NGAPVPVPPK RTVKRNIPKL DAQRLISERG LPALRHVFDK AKFKGKGHEA EDLKMLIRHM EHWAHRLFPK LQFEDFIDRV EYLGSKKEVQ TCLKRIRLDL PILHEDFVSN NDEVAENNEH DVTSTELDPF LTNLSESEMF ASELSRSLTE EQQQRIERNK QLALERRQAK LLSNSQTLGN DMLMNTPRAH TVEEVNTDED QKEESNGLNE DILDNPCNDA IANTLNEEET LLDQSFKNVQ QQLDATSRNI TEAR
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TIPIN Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TIPIN (TIMELESS Interacting Protein (TIPIN))
- Alternative Name
- TIPIN (TIPIN Products)
- Synonyms
- 1110005A05Rik Protein, 1110018P21Rik Protein, RGD1564084 Protein, MGC82649 Protein, zgc:91928 Protein, tipin Protein, TIMELESS interacting protein Protein, timeless interacting protein Protein, timeless interacting protein S homeolog Protein, timeless interacting protein L homeolog Protein, TIPIN Protein, Tipin Protein, tipin.S Protein, tipin Protein, tipin.L Protein
- Background
- TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Recombinant human TIPIN, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 36.9kDa (324 aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_060328
- UniProt
- Q9BVW5
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