HNRNPAB Protein (AA 1-285) (His tag)

Catalog No. ABIN5853296

Product Details

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Protein Type: Recombinant

Protein Characteristics: AA 1-285

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HNRNPAB protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEAGEE QPMETTGATE NGHEAVPEGE SPAGAGTGAA AGAGGATAAP PSGNQNGAEG DQINASKNEE DAGKMFVGGL SWDTSKKDLK DYFTKFGEVV DCTIKMDPNT GRSRGFGFIL FKDAASVEKV LDQKEHRLDG RVIDPKKAMA MKKDPVKKIF VGGLNPEATE EKIREYFGEF GEIEAIELPM DPKLNKRRGF VFITFKEEEP VKKVLEKKFH TVSGSKCEIK VAQPKEVYQQ QQYGSGGRGN RNRGNRGSGG GGGGGGQGST NYGKSQRRGG HQNNYKPY

Purity: > 95 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In PBS containing 30 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Alternative Name: HNRNPAB (HNRNPAB Products)

Synonyms: fd36h02 Protein, wu:fd36h02 Protein, ABBP1 Protein, HNRPAB Protein, 3010025C11Rik Protein, CBF-A Protein, Cgbfa Protein, Hnrpab Protein, A1F-C1 Protein, hm:zeh1271 Protein, hnrpab Protein, wu:fa18g02 Protein, wu:fb07b06 Protein, wu:fb16c05 Protein, zeh1271 Protein, HNRNP A/B Protein, heterogeneous nuclear ribonucleoprotein A/Bb Protein, heterogeneous nuclear ribonucleoprotein A/B Protein, heterogeneous nuclear ribonucleoprotein A/Ba Protein, heterogeneous nuclear ribonucleoprotein A/B L homeolog Protein, hnrnpabb Protein, hnrnpab Protein, HNRNPAB Protein, Hnrnpab Protein, hnrnpaba Protein, hnrnpab.L Protein

Background: HNRNPAB belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPAB, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Recombinant human HNRNPAB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 33 kDa (308aa) confirmed by MALDI-TOF

NCBI Accession: NP_004490

UniProt: Q99729