UBE2R2 Protein (AA 1-238) (His tag)
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- Target See all UBE2R2 Proteins
- UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-238
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2R2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAQQQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product UBE2R2 Protein
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Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2) (AA 1-238) protein (His tag)
UBE2R2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2) (AA 1-238) protein (GST tag)UBE2R2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2) protein (Myc-DYKDDDDK Tag)UBE2R2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))
- Alternative Name
- uBE2R2 (UBE2R2 Products)
- Synonyms
- CDC34B Protein, E2-CDC34B Protein, UBC3B Protein, zgc:92307 Protein, UBE2R2 Protein, 1200003M11Rik Protein, Cdc34b Protein, Ubc3b Protein, cdc34b Protein, e2-cdc34b Protein, ubc3b Protein, ubiquitin conjugating enzyme E2 R2 Protein, ubiquitin-conjugating enzyme E2R 2 Protein, ubiquitin-conjugating enzyme E2R 2 pseudogene Protein, UBE2R2 Protein, ube2r2 Protein, LOC465050 Protein, Ube2r2 Protein
- Background
- UBE2R2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This protein is a protein similar to the E2 ubiquitin conjugating enzyme uBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. Recombinant human uBE2R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.6kDa (261aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_060281
- UniProt
- Q712K3
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