APOA5 Protein (AA 24-366) (His tag)

Catalog No. ABIN5853437

Product Details

Target: APOA5 (Apolipoprotein A-V (APOA5))

Protein Type: Recombinant

Protein Characteristics: AA 24-366

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This APOA5 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSRKGFWDY FSQTSGDKGR VEQIHQQKMA REPATLKDSL EQDLNNMNKF LEKLRPLSGS EAPRLPQDPV GMRRQLQEEL EEVKARLQPY MAEAHELVGW NLEGLRQQLK PYTMDLMEQV ALRVQELQEQ LRVVGEDTKA QLLGGVDEAW ALLQGLQSRV VHHTGRFKEL FHPYAESLVS GIGRHVQELH RSVAPHAPAS PARLSRCVQV LSRKLTLKAK ALHARIQQNL DQLREELSRA FAGTGTEEGA GPDPQMLSEE VRQRLQAFRQ DTYLQIAAFT RAIDQETEEV QQQLAPPPPG HSAFAPEFQQ TDSGKVLSKL QARLDDLWED ITHSLHDQGH SHLGDP

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing , 10 % glycerol, 0.4M urea

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: APOA5 (Apolipoprotein A-V (APOA5))

Alternative Name: APOA5 (APOA5 Products)

Synonyms: APOAV Protein, RAP3 Protein, 1300007O05Rik Protein, Apoav Protein, apo-AV Protein, apoA-V Protein, APOA5 Protein, MGC140487 Protein, rap3 Protein, apoav Protein, apoa-v Protein, apolipoprotein A5 Protein, apolipoprotein A-V Protein, apolipoprotein A5 L homeolog Protein, APOA5 Protein, Apoa5 Protein, apoa5.L Protein, apoa5 Protein

Background: APOA5 is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. Recombinant human APOA5 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Molecular Weight: 41.3kDa (366aa)

NCBI Accession: NP_443200

UniProt: Q6Q788

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism