STEAP4 Protein (AA 1-152) (His tag)
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- Target See all STEAP4 Proteins
- STEAP4 (STEAP Family Member 4 (STEAP4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-152
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This STEAP4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS VVFGSRNPQK TTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product STEAP4 Protein
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STEAP Family Member 4 (STEAP4) (AA 1-470) protein (Strep Tag)
Crystallography grade STEAP4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
STEAP Family Member 4 (STEAP4) (AA 1-459) protein (Strep Tag)Crystallography grade STEAP4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
STEAP Family Member 4 (STEAP4) protein (Myc-DYKDDDDK Tag)STEAP4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- STEAP4 (STEAP Family Member 4 (STEAP4))
- Alternative Name
- STEAP4 (STEAP4 Products)
- Synonyms
- STAMP2 Protein, TIARP Protein, TNFAIP9 Protein, MGC68826 Protein, STEAP4 Protein, MGC108044 Protein, steap4 Protein, 1110021O17Rik Protein, AI481214 Protein, Tiarp Protein, Tnfaip9 Protein, si:dkey-53p21.1 Protein, zgc:112143 Protein, STEAP4 metalloreductase Protein, STEAP4 metalloreductase L homeolog Protein, metalloreductase STEAP4 Protein, STEAP family member 4 Protein, STEAP4 Protein, steap4.L Protein, Steap4 Protein, steap4 Protein, LOC100136336 Protein, LOC100353852 Protein
- Background
- STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+),using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human STEAP4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 20.6kDa (188aa)
- NCBI Accession
- NP_078912
- UniProt
- Q687X5
- Pathways
- Transition Metal Ion Homeostasis
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