LMX1B Protein (AA 1-395) (His tag)
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- Target See all LMX1B Proteins
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-395
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LMX1B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMDIATGP ESLERCFPRG QTDCAKMLDG IKMEEHALRP GPATLGVLLG SDCPHPAVCE GCQRPISDRF LMRVNESSWH EECLQCAACQ QALTTSCYFR DRKLYCKQDY QQLFAAKCSG CMEKIAPTEF VMRALECVYH LGCFCCCVCE RQLRKGDEFV LKEGQLLCKG DYEKEKDLLS SVSPDESDSV KSEDEDGDMK PAKGQGSQSK GSGDDGKDPR RPKRPRTILT TQQRRAFKAS FEVSSKPCRK VRETLAAETG LSVRVVQVWF QNQRAKMKKL ARRHQQQQEQ QNSQRLGQEV LSSRMEGMMA SYTPLAPPQQ QIVAMEQSPY GSSDPFQQGL TPPQMPGNDS IFHDIDSDTS LTSLSDCFLG SSDVGSLQAR VGNPIDRLYS MQSSYFAS
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product LMX1B Protein
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LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-372) protein (GST tag)
LMX1B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-110) protein (GST tag)LMX1B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-402) protein (Strep Tag)Crystallography grade LMX1B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-395) protein (Strep Tag)Crystallography grade LMX1B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- iquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
- Alternative Name
- LMX1B (LMX1B Products)
- Synonyms
- LMX1.2 Protein, NPS1 Protein, LMX Protein, LMX1 Protein, LMX1.1 Protein, lmx1b Protein, lmx1b.1 Protein, Xlmx1b Protein, lmx1b.2 Protein, LIM homeobox transcription factor 1 beta Protein, LIM homeobox transcription factor 1, beta b Protein, LIM homeobox transcription factor 1, beta, gene 1 S homeolog Protein, LIM homeobox transcription factor 1, beta a Protein, LMX1B Protein, Lmx1b Protein, lmx1bb Protein, lmx1b.1.S Protein, lmx1ba Protein
- Background
- LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human LMX1B protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 46.5 kDa (418 aa)
- NCBI Accession
- NP_002307
- UniProt
- O60663
- Pathways
- Dopaminergic Neurogenesis
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