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DPY30 Protein (AA 1-99) (His tag)

DPY30 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5853858
  • Target See all DPY30 Proteins
    DPY30 (Dpy-30 Homolog (DPY30))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-99
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DPY30 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product DPY30 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 30 % glycerol, 2  mM DTT
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    DPY30 (Dpy-30 Homolog (DPY30))
    Alternative Name
    DPY30 (DPY30 Products)
    Synonyms
    HDPY-30 Protein, Saf19 Protein, 2810410M20Rik Protein, C87842 Protein, Aip1 Protein, dpy-30, histone methyltransferase complex regulatory subunit Protein, dpy-30 histone methyltransferase complex regulatory subunit Protein, DPY30 Protein, Dpy30 Protein
    Background
    As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. This protein may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. Recombinant human DPY30 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    13.6 kDa (122aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_115963
    UniProt
    Q9C005
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